<p><table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td class="down" id="feedsTitleFEEDS_12447656431" align="center"><table height="100%" cellspacing="0" cellpadding="0" border="0"><tbody><tr class="sysHand"><td><div class="sysBr500 title"><a href="http://blog.sina.com.cn/u/4a319dcb010005us" target="_blank">一老美写的B题第二问的答案</a></div></td></tr></tbody></table></td></tr><tr><td class="itemBox"><table class="author" cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td><img class="man" src="http://image2.sina.com.cn/blog/tmpl/v3/theme/images/sun.gif" alt=""/><span class="time">2006-09-17 07:51:58</span></td></tr></tbody></table></td></tr><tr id="feedsItemFEEDS_12447656431"><td class="itemBox"><table class="dashed" cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td></td></tr></tbody></table><table cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td><div class="sysBr500 text"><div>搜出来篇论文，准确地说是一老美的一本书里的一个例子<br/>与B题第二问完全相同</div><div>可惜是用SAS做的 不知有谁可以看懂 请与我交流一下 谢</div><div>地址是<a href="http://www.biostat.harvard.edu/~fitzmaur/ala/">http://www.biostat.harvard.edu/~fitzmaur/ala/</a><br/>进去后点<a href="http://album.sina.com.cn/pic/4a319dcb020009qg" target="_blank"><img src="http://album.sina.com.cn/pic/4a319dcb020009qg" border="0" alt=""/></a>，</div><div>接着点<a href="http://album.sina.com.cn/pic/4a319dcb020009qi" target="_blank"><img src="http://album.sina.com.cn/pic/4a319dcb020009qi" border="0" alt=""/></a>，向下拉，你会看到<a href="http://album.sina.com.cn/pic/4a319dcb020009ql" target="_blank"><img height="24" src="http://album.sina.com.cn/pic/4a319dcb020009ql" width="485" border="0" style="WIDTH: 485px; HEIGHT: 24px;" alt=""/></a></div><div><a href="http://album.sina.com.cn/pic/4a319dcb020009qj" target="_blank"></a></div><div>接下来是程序：</div><div>Linear Mixed Effects Model (Random Intercept and Slopes)</div><div> </div><div> </div><div>data cd4;<br/> infile 'cd4.dat';<br/> input id group age sex week logcd4;</div><div>****************************************************************;</div><div>* Create new variable combining groups 1, 2, and 3 *;</div><div>****************************************************************;</div><div>trt=0;<br/>if (group=4) then trt=1;</div><div>week_16=max(week - 16, 0);<br/>w16=week_16 - week;</div><div><br/>title1 Mixed Effects Model for log CD4;<br/>title2 AIDS Clinical Trial Group (ACTG) 193A Study;</div><div>proc mixed method=reml noclprint=10 covtest;<br/> class id;<br/> model logcd4 = week week_16 trt*week trt*week_16 / s chisq;<br/> random intercept week week_16 / subject=id type=un g gcorr;<br/>run;</div><div><Selected Output></div><div> </div><br/><br/><a href="http://blog.sina.com.cn/u/4a319dcb010005us" target="_blank" style="FONT-STYLE: italic;">点击此处查看原文</a></div></td></tr></tbody></table><table class="dashed" cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td></td></tr></tbody></table><table class="function" cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td><a href="http://blog.sina.com.cn/u/4a319dcb010005us" target="_blank">固定链接</a>┆ <a title="提示：评论数每隔1~2小时刷新一次" href="http://blog.sina.com.cn/u/4a319dcb010005us#comment" target="_blank">评论(3)</a>┆ <a href="http://blog.sina.com.cn/control/writing/scriber/article_add_by_quote.php?blog_id=4a319dcb010005us" target="_blank">引用</a>┆ <a title="提示：阅读数每隔1~2小时刷新一次" href="http://blog.sina.com.cn/myblog/article/article_reader.php?blog_id=4a319dcb010005us" target="_blank">阅读(343)</a></td></tr></tbody></table></td></tr></tbody></table><table cellspacing="0" cellpadding="0" width="100%" border="0"><tbody><tr class="line"><td></td></tr></tbody></table><table cellspacing="0" cellpadding="0" border="0"><tbody><tr><td class="down" id="feedsTitleFEEDS_12447656432" align="center"><table height="100%" cellspacing="0" cellpadding="0" border="0"><tbody><tr class="sysHand"><td><div class="sysBr500 title"><a href="http://blog.sina.com.cn/u/4a319dcb010005ue" target="_blank">中途</a></div></td></tr></tbody></table></td></tr><tr><td class="itemBox"><table class="author" cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td><img class="man" src="http://image2.sina.com.cn/blog/tmpl/v3/theme/images/sun.gif" alt=""/><span class="time">2006-09-16 14:20:53</span></td></tr></tbody></table></td></tr><tr id="feedsItemFEEDS_12447656432"><td class="itemBox"><table class="dashed" cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td></td></tr></tbody></table><table cellspacing="0" cellpadding="0" align="center" border="0"><tbody><tr><td><div class="sysBr500 text"><div>无意中把B组第二问的官方资料找出来了<br/>就是美国1997年193A的原材料</div><div>原文如下：</div><div> </div><div>Repeated CD4 counts data from AIDS clinical trial.</div><div>Source: AIDS Clinical Trial Group 193A Study.<br/>Data courtesy of Dr. Keith Henry.</div><div>Reference: Henry, K., Erice, A., Tierney, C., Balfour, H.H. Jr, Fischl, M.A.,<br/>Kmack, A., Liou, S.H., Kenton, A., Hirsch, M.S., Phair, J., Martinez, A.<br/>and Kahn J.O. for the AIDS Clinical Trial Group 193A Study Team (1998).<br/>A randomized, controlled, double-blind study comparing the survival benefit of<br/>four different reverse transcriptase inhibitor therapies (three-drug, two-drug,<br/>and alternating drug) for the treatment of advanced AIDS. Journal of Acquired<br/>Immune Deficiency Syndromes and Human Retrovirology, 19, 339-349.</div><div><br/>Description:</div><div>The data are from a randomized, double-blind, study of AIDS patients with<br/>advanced immune suppression (CD4 counts of less than or equal to 50 cells/mm^3).<br/> atients in AIDS Clinical Trial Group (ACTG) Study 193A were randomized to<br/>dual or triple combinations of HIV-1 reverse transcriptase inhibitors.<br/>Specifically, patients were randomized to one of four daily regimens containing<br/>600mg of zidovudine: zidovudine alternating monthly with 400mg didanosine;<br/>zidovudine plus 2.25mg of zalcitabine; zidovudine plus 400mg of didanosine;<br/>or zidovudine plus 400mg of didanosine plus 400mg of nevirapine (triple therapy).<br/>Measurements of CD4 counts were scheduled to be collected at baseline and at<br/>8-week intervals during follow-up. However, the CD4 count data are unbalanced<br/>due to mistimed measurements and missing data that resulted from skipped visits<br/>and dropout. The number of measurements of CD4 counts during the first 40<br/>weeks of follow-up varied from 1 to 9, with a median of 4.<br/>The response variable is the log transformed CD4 counts, log(CD4 counts +</div></div></td></tr></tbody></table></td></tr></tbody></table></p><p>引自：<a href="http://blog.sina.com.cn/u/1244765643">http://blog.sina.com.cn/u/1244765643</a></p> |
发表于 2006-9-20 00:27:18
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